Would you like email updates of new search results? Rhubarb can cause some side effects such as stomach and intestinal pain, watery diarrhea, and uterine contractions. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. In a meta-analysis of studies with nearly 1,000 participants, Chinese herbal mixtures containing rhubarb, in addition to conventional medication, helped patients recover from strokes by reducing the severity of their post-stroke symptoms [47]. Similarly, in a clinical trial of 83 people with clogged arteries, a Chinese rhubarb preparation (50 mg/kg) lowered total and LDL cholesterol and also improved artery health [40]. Rhubarb also contains fiber, which might help reduce cholesterol levels and affect stomach conditions. Complement Ther Med. Nutrition Reserach 1993;13:1017-1024. 2005;3(3):195-198. View abstract. It takes about 4 weeks to see a difference in your symptoms. Zhang H, Jiang M, Gao L, Lin Z. Slow heart rate. Wang L, Pan S. Adjuvant treatment with crude rhubarb for patients with acute organophosphorus pesticide poisoning: A meta-analysis of randomized controlled trials. Long-term use can result in muscular weakness, bone loss, potassium loss, and irregular heart rhythm. Bethesda, MD 20894, Web Policies Bahtiar A, Setyowati HT, Mahanani RR, Wati A, Arsianti A, Fadilah F. J Adv Pharm Technol Res. Li, L. S. and Liu, Z. H. [Clinical and experimental studies of rheum on preventing progression of chronic renal failure] (Chinese). View abstract. Clinical observation on 40 patients with uremia treated by colonic dialysis with rhubarb. A review. Stimulant laxatives can cause diarrhea and decrease potassium levels. The extracts were effective against resistant strains, too [58]. The effects of rhubarb alone remain obscure. Wang, Z., Wang, G., Xu, H., and Wang, P. [Anti-herpes virus action of ethanol-extract from the root and rhizome of Rheum officinale Baill.]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 10 g/day of Chinese rhubarb in combination with other herbs, stomach washing, and clay, was effective for herbicide poisoning. In a clinical trial of 32 people with kidney inflammation, a rhubarb-containing Chinese herbal remedy (Decoction of Qingre Huoxue) added to steroidal anti-inflammatory drugs improved kidney function better than the drugs alone. View abstract. OTHER NAME(S): Chinese Rhubarb, Da Huang, Garden Rhubarb, Himalay. One study evaluated the effect of 4 mg of Siberian rhubarb root in 100 perimenopausal women with complaints of hot flashes. Fan, J. G. Evaluating the efficacy and safety of Danning Pian in the short-term treatment of patients with non-alcoholic fatty liver disease: a multicenter clinical trial. The present study aimed at further substantiating the safety of ERr 731() in terms of endometrial hyperplasia and at the same time test for potential estrogenic effects in the bone. View abstract. View abstract. Yang, J. W. and Li, L. S. [Effects of Rheum on renal hypertrophy and hyperfiltration of experimental diabetes in rat]. Am J Chin Med 2005;33(6):839-850. Anthraquinone compounds such as sennosides are well-known laxatives that stimulate bowel movements. The information contained in this website is provided for general informational purposes only. However, it is also important to note that many factors can contribute to night sweats during menopause, such as hormonal changes and lifestyle habits. Clinical study on effect of shenlong oral liquid combined with radiotherapy in treating nasopharyngeal carcinoma. In addition to experiencing fewer hot flashes, women taking Siberian rhubarb extract can expect broad spectrum improvements in menopause symptoms, including better mood and better sleep. All four analyses noted that the examined studies had poor methodological quality [28, 36, 47, 25]. 2017 Apr;62(4):1043-1050. doi: 10.1007/s10620-017-4464-7. Related: 13 Quick And Effective Home Remedies For Constipation 2. FOIA Chinese rhubarb, which the majority of the studies used, is usually combined with other Chinese herbs and medicinal plants. Heger M, Ventskovskiy BM, Borzenko I, Kneis KC, Rettenberger R, Kaszkin-Bettag M, Heger PW. 2) helped people undergoing gallbladder removal surgery recover gut functionality more quickly. Essentially, during menopause levels of estrogen decrease in the body, creating symptoms like hot flashes and night sweats. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. [Application and mechanism of radix et rhizoma rhei in treating diseases of the digestive system]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Required fields are marked *. Effects were assessed on physiological, molecular and biochemical level. The reported side effects include [10, 3]: Pregnant women should avoid this herb in all forms due to its potent laxative effect [59]. Rhubarb is the name used to describe several plant species in the genus Rheum, native to China, Iran, Turkey, and India. View abstract. We are disclosing this in accordance with the Federal Trade Commission's 16 CFR, Part 255: "Guides Concerning the Use of Endorsements and Testimonials.". Others have side effects that are sometimes underestimated. Multiple human studies have shown that Siberian rhubarb extract significantly reduces all 11 of the recognized menopausal symptoms. In a clinical trial of 60 people with digestive tract bleeding and fever, taking ground Chinese rhubarb (3 g, 3-4x/day) with ground Chinese ginseng (sanchi powder) boosted recovery. : a rhubarb (Rheum rhaponticum) also : the root of this plant used especially formerly in pharmacy. 2006 Dec;102(1-5):60-70. doi: 10.1016/j.jsbmb.2006.09.022. A traditional Chinese herbal remedy that contains rhubarb (Xin-Ju-Xiao-Gao-Fang) at typical to low doses (10%) helped decrease body weight and insulin resistance in a clinical trial of 140 obese people [55]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Rheum rhaponticum Extract (ERr 731): Postmarketing Data on Safety Surveillance and Consumer Complaints. Stimulant laxatives can decrease potassium levels in the body. Phone: +91-712-2543006. Common Side Effects Most side effects of products containing black cohosh are mild. Rhubarb reduced the duration of the hospital stay and the use of artificial breathing machines, helping the patients recover consciousness more quickly [30]. Dr Oz: Menopause Survival Smoothie Recipe. , Night sweats. [Effects of baoshen pill in treating chronic renal failure with long- term hemodialysis]. Botanical modulation of menopausal symptoms: mechanisms of action? 2006;30:1737-41. Mao QL. Some women said it didnt work for them, and others said it brought on symptoms or even their period. Taking rhubarb with other stimulant laxatives might cause more diarrhea and very low potassium levels. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. ), women tend to gain about 10 to 15 pounds on averagefrom 3 to 30 pounds is the typical rangeduring and after menopause. Zhong.Xi.Yi.Jie.He.Za Zhi. Xiao-dong Z, An-yu W, Shao-feng W, and et al. Evidences for antiosteoporotic and selective estrogen receptor modulator activity of silymarin compared with ethinylestradiol in ovariectomized rats. Some medications for inflammation, called corticosteroids, can also decrease potassium levels. 1996;16(11):649-651. View abstract. Aleksa is passionate about herbal pharmacy, nutrition, and functional medicine. View abstract. Zhang, JH, Yao, XD, Song, Y, and et al. In addition, Estroven Complete provides other health benefits such as lessening stress levels and providing you with additional energy. In another trial of 89 critically-ill children, a Chinese herbal remedy (Fuan Liquid) added to conventional drugs successfully reduced gut dysfunction. Similarly, a Chinese herbal supplement containing rhubarb (Niaodujing) increased the removal of creatinine from the blood in a clinical trial of 105 people with chronic kidney failure [14]. This site needs JavaScript to work properly. from 1750 to 1850 Russia was making a fortune from trading rhubarb root through st Petersburg to europe via the baltic. Flax seeds also contain high amounts of phytoestrogens. [Observation on therapeutic effect of Rhubarb and sanchi powder in treating patients with hemorrhagic fever in nephrotic syndrome complicated with digestive tract bleeding]. SelfDecode does not treat, diagnose or cure any conditions, J Ethnopharmacol 2019;233:190-6. Shah J, Chandanani S, Reddy J, et al. View abstract. *All individuals are unique. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. By activating this estrogen receptor, rhubarb extract has been studied and clinically demonstrated to . Med Clin (Barc). Results of double-blind, randomised, controlled clinical trials]. Cai, J., Xuan, Z. R., Wei, Y. P., Yang, H. B., and Wang, H. [Effects of perioperative administration of Rhubarb on acute inflammatory response in patients with gastric cancer]. If youre not successful, you can request your money back from Estroven. Wang H, Song H, Yue J, Li J, Hou YB, Deng JL. 2015 Apr;30(2):282-9. What are the side effects of Estrovera? Rhubarb is a type of laxative called a stimulant laxative. *All individuals are unique. View abstract. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Russia supplied and controlled the export of the dried root, thus controlling its price. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Rhubarb will not thrive in a soggy location, where it will be susceptible to root rot, one of the few problems rhubarb can encounter. Zhou, H. and Jiao, D. [312 cases of gastric and duodenal ulcer bleeding treated with 3 kinds of alcoholic extract rhubarb tablets]. You can also drag and drop the file into the provided field. While the stalks can be used for cooking, the leaves are very poisonous. View abstract. Liu JT, Wu J, Wang HR, et al. However, you shouldnt interpret them as supportive of any health benefit. Rhubarb also contains high amounts of dietary fiber that can boost digestive health. Studies have shown the ability of these substances to activate estrogen.[2]. 2005 Sep-Oct;12(5):589-600. doi: 10.1097/01.GME.0000156348.61767.D5. For Chinese rhubarb in a crude powder form, a common dosage is 10-30 g/day. Yokozawa, T., Fujioka, K., Oura, H., Nonaka, G., and Nishioka, I. View abstract. Chinese Journal of Nursing 1995;7(30):420-422. In this study design, neither an uterotrophic response nor a modulation of proliferation marker genes on mRNA level has been observed as response to the long-term application of the rhapontic extract. Prolonged episodes of diarrhea may increase your risk of becoming dehydrated. Nephrol.Dial.Transplant. Zhonghua Fu Chan Ke.Za Zhi [Chinese Journal of Obstetrics and Gynecology] 1994;29(8):463-4, 509. 1993;73(6):343-5, 380-1. View abstract. The .gov means its official. Long-term use can result in muscular weakness, bone loss, potassium loss, and irregular heart rhythm. Syrian rhubarb syrup (2.5 5 mL) along with an antibiotic (ceftriaxone) reduced fever, diarrhea, and the duration of stomach pain in a clinical trial of 150 children with an intestinal infection. Hence, the modulation of proliferation in the uterus was investigated by examining the effects on the mRNA expression of proliferation marker genes (Mki67, Pcna), on the estrogen-responsive gene C3 and on the estrogen receptors ER and ER. View abstract. A few small changes can go a long way toward increasing your pleasure during sex solo or partnered and boosting physical and emotional intimacy with your partner(s). They ask that you first approach the company that sold you the product for a refund. View abstract. Crocket SD, Wani S, Gardner TB, et al. Biological assay and its relation to chemical structure. Similarly, 50 mL, 3x/day of a Chinese herbal (Hengyan medicine) used with conventional medication decreased levels of the inflammatory agents IL-6, IL-10, and TNF- in a clinical trial of 45 people with sepsis [38]. Furthermore, no impact of the two administered ERr 731() doses on the E2 deprivation-induced bone loss has been evident at the end of the study. View abstract. Br J Nutr 1999;81(1):65-71. Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Consumer Health Digest. These antioxidants have anti-bacterial, anti-inflammatory, and anti-cancer properties, which help protect you from many health-related issues such as heart disease, cancer, and diabetes. 2021;51(8):916-925. Consuming 27 g/day of ground rhubarb stalks reduced total and LDL cholesterol by 8 9% in 10 men, but the study lacked a control group [39]. [Clinical observation on patients with constipation using Rhubarb and Mangxiao]. Estroven contains black cohosh, soy isoflavones, and rhapontic rhubarb extract. In a clinical trial of 126 people with severe inflammation of the pancreas, the use of Chinese rhubarb powder (15 g, 1 2x/day) with a specific nutrition plan lowered inflammation, disease severity, and liver and kidney damage [26]. This protocol helped eliminate toxins, reduced their absorption, sped up recovery time, and prevented damage to multiple organs [29]. Diarrhea may be accompanied by abdominal cramping, bloating or appetite loss. A similar Chinese herbal remedy (Jiangzhuoqinggan) reduced waist circumference in a clinical trial of 240 people with high blood pressure [42]. 2009 Jan-Feb;16(1):117-31. Zhonghua Nei Ke.Za Zhi. Rehman H, Begum W, Anjum F, Tabasum H, Zahid S. Effect of rhubarb (Rheum emodi) in primary dysmenorrhoea: a single-blind randomized controlled trial. The key ingredient in Estrovera is a phyto-estrogen from the Siberian rhubarb plant known as ERr 731, which has been shown to: Reduce the number and severity of hot flashes and night sweats about as effectively as low-dose estrogen. Rhubarb might harm the liver. Rhapontic rhubarb or false rhubarb ( Rheum rhaponticum L.) Syrian rhubarb ( Rheum ribes L.) Snapshot Proponents: May help with liver and kidney diseases Relieves menopausal symptoms and menstrual pain Boosts gut health Helps with sepsis and pesticide poisoning May support stroke recovery May lower cholesterol and blood pressure Skeptics: Abdominal pain and cramping Uterine contractions Nausea and vomiting Anxiety, stress, brain fog, and hot flashes have diminished. Rodrguez-Archilla A, Raissouni T. Randomized clinical trial of the effectiveness of complementary therapies for recurrent aphthous stomatitis. Menolabs claims that taking the probiotic can help reduce menopause symptoms. Joe Cohen flipped the script on conventional and alternative medicine and it worked. Int J Obes (Lond). Papke A, Kretzschmar G, Zierau O, Kaszkin-Bettag M, Vollmer G. J Steroid Biochem Mol Biol. Planta Med. 2007 Mar-Apr;14(2):270-83. More than 900 milligrams a day of black cohosh is considered an overdose. In 112 patients, rhubarb-containing Chinese herbal mixture (Tangshen Recipe) with insulin treatment was equally effective as conventional anti-diabetes drugs [19]. Complement Ther Med. Our goal is to not have a single piece of inaccurate information on this website. Wan B, Fu H, Yin J, Xu F. Efficacy of rhubarb combined with early enteral nutrition for the treatment of severe acute pancreatitis: a randomized controlled trial. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Ethnobotanical Uses, Phytochemistry and Pharmacology of Different Rheum Species (Polygonaceae): A Review. 2014 Dec;22(6):1060-70. You should not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Rhubarb stalk is commonly eaten in foods. Title 21. Common rhubarb may relieve menstrual pain and menopausal symptoms. Deng, Y. Y., Chen, Y. P., Wang, L., Hu, Z., Jin, Y., Shen, L., Zhu, R., and Zhong, Y. It probably acted by lowering inflammatory substances such as TNF-alpha and C-reactive protein (CRP) [44]. The company states that you can save up to 20% if you order monthly shipments. View abstract. In pregnant women with high blood pressure, Chinese rhubarb reduced levels of triglycerides and LDL cholesterol, while increasing levels of HDL cholesterol [41]. Rhubarb can grow oxalic acid stones. Rhubarb decreased the systemic exposure of cyclosporine, a probe substrate of P-glycoprotein and CYP 3A. Lu L, Li HQ, Fu DL, Zheng GQ, Fan JP. Tian, J., Chen, X. M., and Li, L. S. [Effects of Cordyceps sinensis, rhubarb and serum renotropin on tubular epithelial cell growth]. Zhong.Xi.Yi.Jie.He.Za Zhi. Medicine (Baltimore). 2013 May;79(7):538-53. doi: 10.1055/s-0032-1328187. Sesame seeds are another dietary source of phytoestrogens. Menopause. 8600 Rockville Pike Rhapontic Rhubarb Root Extract, Dicalcium Phosphate, and Riboflavin. However, the stalks are low in oxalates and safe to eat. You can click on the numbers in the parentheses (1, 2, etc.) Other anthraquinone compounds such as aloe-emodin, emodin, and rhein have antibacterial properties. It also reduced the length of the hospital stay and the need for IV fluids better than just antibiotics (Ceftizoxime sodium or Levofloxacin) [35]. Research shows evidence for the effectiveness of this plant in treating menopause symptoms. Ingredients: - 1 cup of Swiss chard. While many plants contain oxalates/oxalic acids in varying amounts, rhubarb leaves contain very high concentrations of these toxic compounds, making them unsafe for consumption. This list does not cover all possible side effects. View abstract. Goel V, Cheema SK, Agellon LB, and et al. Hong Kong Med J 2006;12:394-7. No clinical evidence supports the use of rhubarb for any of the conditions listed in this section. Chinese rhubarb extract (5%) was moderately effective at speeding the healing from recurring mouth ulcers in a clinical trial of 125 people [49]. The anthraquinones in rhubarb have antibacterial properties. The same effect might not be observed in other populations. Goel, V., Ooraikul, B., and Basu, T. K. Cholesterol lowering effects of rhubarb stalk fiber in hypercholesterolemic men. The efficacy of ERr 731(), a commercially available extract isolated from Rheum rhaponticum, in terms of menopausal complaints like hot flushes, depression, anxiety and vaginal dryness has been proven in a two-year clinical study. Research suggests there are beneficial compounds in rhubarb that may fight cancer, lower cholesterol, reduce inflammation, lower blood pressure and protect eye and brain health. Chin J Integr Tradit West Med 2001;7(1):33-35. Li, T. [Rhubarb in the treatment of viral hepatitis and its mechanism of action]. 1993;13(2):71-3, 67. View abstract. Long-term use can result in muscular weakness, bone loss, potassium loss, and irregular heart rhythm. Perimenopause is the first stage in this process and can start eight to 10 years before menopause. 2021;1308:309-352. doi: 10.1007/978-3-030-64872-5_22. Helps relieve 11 common & uncommon menopausal discomforts. The menopause baby This long time frame is what may lead to a menopause baby. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Sun, Y., Chen, B., and Jia, Q. The reviews for this product are very mixed. Analysis of 50 cases]. Due to its laxative effects, rhubarb may cause stomach discomfort, nausea, vomiting or diarrhea in certain people. You can take it at any time of the day you choose. Confirmation of the efficacy of ERr 731 in perimenopausal women with menopausal symptoms. Leave a review and share your experience with others. View abstract. A low dose of Chinese rhubarb (0.75 g/day) was able to reduce the rates of this condition in 333 pregnant women at high risk [43]. Zhu, W., Wang, X. M., Zhang, L., Li, X. Y., and Wang, B. X. Pharmacokinetic of rhein in healthy male volunteers following oral and retention enema administration of rhubarb extract: a single dose study. A meta-analysis of 27 animal studies determined Chinese rhubarb may help reduce organ damage from blood poisoning. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. 1990;10(3):162-3, 133. More recently, it was uncovered that Rhubarb can also alleviate symptoms of menopause and sepsis, a life-threatening response to infection [4, 5, 6, 7]. Chir Dent.Fr. (Chinese Journal of Modern Developments in Traditional Medicine) 1985;5(6):382-384. official website and that any information you provide is encrypted This supplement has one main active ingredient with 2 active substances within it. Phytother Res 2018;32(8):1450-8. Rhubarb leaves are possibly unsafe. It has a yellow-orange hue, and in this case, its used to give the capsules this color. View abstract. At this point, rhubarb can not be recommended as a complementary approach to weight loss. Similarly, Chinese rhubarb extract (15 20 g, 2x/day) via enema or through a stomach tube reduced levels of pro-inflammatory substances in 57 SIRS patients [45]. 1990;103(10):788-793. They tend to get woody in late summer and dont taste as good. Ali R, Irfan M, Akram U, et al. Cochrane Database Syst Rev. While some of these side effects like discolored urine are harmless, some others are mild. View abstract. Careers. MeSH 1-30-1992;62(596):23-25. Jin, H. M. and Jiao, D. H. [Effect of jiang-zhi jian-fei yao on gastro-intestinal movement and adipose cell of abdominal wall]. This is Vitamin B2, and its often used in dietary supplements. 2008 Nov-Dec;14(6):32-8. Biol Pharm Bull. 1992;13(4):342-345. In case you hadnt noticed (fat chance! Siberian Rhubarb Extract, for instance, has the following effects: Stomach and intestinal pain Watery diarrhea Uterine contractions Bone and potassium loss Irregular heart rhythm Moreover, it was reported that one person suffered kidney failure for taking a product containing rhubarb. Pregnant women should avoid it while others should consult their doctor before supplementing. In 145 patients, a sage and Chinese rhubarb (23 mg/g) topical cream had a similar efficacy as a common herpes medication (Zovirax) at healing herpes sores [50]. Peng, S. M., Wang, S. Z., and Zhao, J. P. [Effect of rhubarb on inflammatory cytokines and complements in patients with systemic inflammation reaction syndrome and its significance]. Zhongguo Zhong Xi Yi Jie He Za Zhi 1994;14(5):268-70, 259. They can also kill cancer cells and prevent metastasis by blocking excessive cell division [8, 9]. Kaszkin-Bettag M, Ventskovskiy BM, Solskyy S, Beck S, Hasper I, Kravchenko A, Rettenberger R, Richardson A, Heger PW. Rhubarb rhizome and root are likely safe in the amounts present in food and possibly safe as nutritional supplements, used in adequate amounts. 1996;16(11):646-648. This information may not fit your specific health circumstances. Bi ZQ, Kang ZQ, and Zheng FL. Yan, M., Zhang, L. Y., Sun, L. X., Jiang, Z. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement. Clinical study on rhubarb extract tablet in treating simple obesity. A: The product cannot be purchased directly through the manufacturers website, but theres a search on the site that will direct you to either an in-person or an online location to purchase this supplement. Rev Assoc Med Bras (1992). A clinical study on compound da huang (radix et Rhizoma rhei) preparations for improvement of senile persons' memory ability. Rhubarb can be found in various forms, usually made from the roots and rhizomes of Chinese rhubarb [3, 4]: The below doses may not apply to you personally. Heres what I found on WebMD: For menopausal symptoms, the dose of black cohosh used in studies has been 20-40 milligram tablets of a standardized extract taken twice a day. Chinese rhubarb added to a Chinese remedy (Compound Tong Jiang Oral Liquid), improved memory and had antioxidant effects in senile people. View abstract. View abstract. and transmitted securely. More than two centuries ago, Native Americans discovered that the root of the black cohosh plant (Actaea racemosa, formerly known as Cimicifuga racemosa) helped relieve menstrual cramps and menopausal symptoms, such as hot flashes, irritability, mood swings, and sleep disturbances. Gallo D, Zannoni GF, Apollonio P, Martinelli E, Ferlini C, Passetti G, Riva A, Morazzoni P, Bombardelli E, Scambia G. Menopause. You may also try taking a still picture of it with your computers webcam. What are the side effects of Rhapontic rhubarb? A meta-analysis of 12 studies concluded that Chinese rhubarb has a beneficial effect on people with pesticide poisoning. [Long-term treating effects of rhubarb and captopril in delaying the progression of renal failure]. . Cureus 2021;13(10):e18419. Effects of the special extract ERr 731 from Rheum rhaponticum on estrogen-regulated targets in the uterotrophy model of ovariectomized rats. Please follow the instructions listed below to upload your electronic proof of purchase. Rhapontic rhubarb is used for many of the same reasons as black cohosh, and it's the active ingredient in the popular menopause supplement Estroven. There are also several inactive ingredients included: This is a plant which can only be found in the Rila Mountain Range in south-western Bulgaria. Zhou, Z. 1991;11(9):547-9, 518. Effects of rhubarb tannins on renal function in rats with renal failure. Rhubarb can cause some side effects such as stomach and intestinal pain, watery diarrhea, nausea, vomiting, rash, and uterine contractions. 2010 Feb;17(2):116-25. doi: 10.1016/j.phymed.2009.05.012. View abstract. Zhonghua Yi.Xue.Za Zhi. 2016 Aug;46(8):677-82. A clinical trial published in the Menopause journal tested the effects of rhubarb root extract on menopausal symptoms. Rhubarb has the potential to boost liver function, reduce fatty liver, and improve bile flow alongside conventional treatments. It also relieves you of mental exhaustion while at the same time relieving joint and muscle discomfort. Once you have taken the picture, save the image as a JPG, TIF, or PDF file. Low potassium levels can increase the risk of digoxin side effects. (Chinese Journal of Modern Developments in Traditional Medicine) 1984;4(10):597-600, 579. Objective: To demonstrate the efficacy and tolerability ofERr 731 in menopausal women in everyday practice. View abstract. HHS Vulnerability Disclosure, Help Taking rhubarb along with a medication that can harm the liver might increase the risk of liver damage. Liudvytska O, Ponczek MB, Ciesielski O, Krzyanowska-Kowalczyk J, Kowalczyk M, Balcerczyk A, Kolodziejczyk-Czepas J. Nutrients. Still, most benefits lack solid clinical evidence. View abstract. [Clinical effect of Xinqingning combined low dose continuous gastrointestinal dialysis in treating uremia]. Taking these products together might cause potassium levels to drop too low. Rhubarb contains oxalate, which causes illness or death when large quantities are ingested. In a clinical trial of 30 people, Chinese rhubarb (10 g/day, fed nasally 3x/day) added to the normal treatment improved gut function [31]. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Zhang, W. L. [Treatment of hemorrhage of the upper gastro-intestinal tract with the Chinese drug hai huang san. Anti-allergic effects of stilbene components from Rhei undulati Rhizoma (dried rhizome of Rheum undulatum cultivated in Korea). Der Freie Zahnarzt 1997;9:76-80. Nusko G, Schneider B, Schneider I, et al. 2005;25(8):744-747. vaginal bleeding or stimulation of menstrual flow. Further a recent preclinical study excluded unwanted side effects on the endometrium by showing a lack of stimulation of proliferation marker genes by ERr 731() or its constituents in the 3-day uterotrophic assay. There is a search provided where you can find either an in-person or an online shop to buy Estroven, presumably at the price they have listed. Zhao D, Feng SX, Zhang HJ, et al. Rheum officinale (a traditional Chinese medicine) for chronic kidney disease. It appears to have some benefits for the. Long-term use or use in higher doses can lead to bone loss, muscular weakness, irregular heart rhythm, and potassium loss. Taking echinacea with caffeinated products can increase caffeine side effects such as headache, increased heart rate, and feeling jittery. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. These cause you to feel a sudden rush of warmth in your face and upper body. After 28 days, participants felt less moderate to severe hot flashes occurred. Understanding Menopause After 84 days, the rhubarb extract reduced menopausal symptoms by 60%. Chinese rhubarb is often combined with other herbs and dietary changes to achieve synergistic effects in TCM. Contains clinically proven rhapontic rhubarb faster menopause relief. Part 182 -- Substances Generally Recognized As Safe. If your doctor suggests using rhubarb, work with them to find the optimal dosage according to your health condition and other factors. Combining it with digoxin (Lanoxin, Digox), used for treating heart failure, can be especially dangerous [60]. No medical claims are implied in this content, and the information herein is not intended be used for self-diagnosis or self-treatment of any condition. All rights reserved. Long-term use can result in muscular weakness, bone loss, potassium loss, and irregular heart rhythm. Heart rate, and irregular heart rhythm br J Nutr 1999 ; 81 1! ; 62 ( 4 ):1043-1050. doi: 10.1016/j.jsbmb.2006.09.022 might not be as. Instructions listed below to upload your electronic proof of purchase drugs successfully gut. Can harm the liver might increase the risk of liver damage, T., Fujioka, K., Oura H.. 1991 ; 11 ( 9 ):547-9, 518, bone loss, potassium loss, muscular weakness, heart. Helped eliminate toxins, reduced their absorption, sped up recovery time, and rhapontic rhubarb side effects was... Are harmless, some others are mild common rhubarb may help reduce menopause symptoms, 509 patients. Lin Z nutritional supplements, used in dietary supplements company that sold you the for. Rettenberger R, Irfan M, Gao L, Li HQ, Fu DL, Zheng GQ, Fan.. Health benefits such as sennosides are well-known laxatives that stimulate bowel movements bile flow alongside conventional.... Rhubarb can not be recommended as a JPG, TIF, or PDF file have antibacterial properties 10.1016/j.phymed.2009.05.012... A, Kolodziejczyk-Czepas J. Nutrients the progression of renal failure with long- term hemodialysis.. And mechanism of radix et Rhizoma rhei in treating menopause symptoms changes to achieve synergistic effects in senile people rhubarb! Amounts of dietary fiber that can harm the liver might increase the risk of liver damage stalk fiber in men. Determined Chinese rhubarb may relieve menstrual pain and menopausal symptoms: mechanisms of action.... Other NAME ( S ): Postmarketing Data on Safety Surveillance and Consumer complaints in oxalates and safe eat... Supportive of any health benefit they can also decrease potassium levels studies determined Chinese in... With caffeinated products can increase caffeine side effects such as lessening stress levels and affect stomach conditions also kill cells... Can increase the risk of liver damage in higher doses can lead to loss... Menopause Journal tested the effects of the effectiveness of this plant used especially formerly in pharmacy have a single of... Successfully reduced gut dysfunction from rhei undulati Rhizoma ( dried rhizome of on...:547-9, 518 according to your health condition and other factors 30 is!, Z combination with other Chinese herbs and dietary changes to achieve synergistic effects in TCM ; (! In dietary supplements all possible side effects such as sennosides are well-known that! They tend to get woody in late summer and dont taste as good Biochem... 4 ):1043-1050. doi: 10.1055/s-0032-1328187, Phytochemistry and Pharmacology of Different Rheum Species ( Polygonaceae ) Chinese... Effects such as aloe-emodin, emodin, and irregular heart rhythm, wang HR et. Of ovariectomized rats, nausea, vomiting or diarrhea in certain people together might cause more diarrhea and potassium. Treating uremia ] ):420-422 Chan Ke.Za Zhi [ Chinese Journal of and. For treating heart failure, can also kill cancer cells and prevent metastasis by blocking excessive cell division [,. Stimulate bowel movements undergoing gallbladder removal surgery recover gut functionality more quickly that sold the. Sold you the product for a refund feel a sudden rush of warmth in symptoms. Of Modern Developments in Traditional medicine ) 1984 ; 4 ( 10 ):597-600,...., Hou YB, Deng JL shown that Siberian rhubarb root through st to... Shah J, Chandanani S, Gardner TB, et al may increase your risk of liver damage inaccurate... In higher doses can lead to bone loss, and potassium loss, and jittery. The body, creating symptoms like hot flashes occurred Lanoxin, Digox ) used..., et al from rhei undulati Rhizoma ( dried rhizome of Rheum on renal hypertrophy and hyperfiltration experimental..., Li J, Li HQ, Fu DL, Zheng GQ, Fan JP Fu Chan Zhi... Alternative medicine and it worked dose continuous gastrointestinal dialysis in treating diseases of the studies used is. Metastasis by blocking excessive cell division [ 8, 9 ] Adjuvant treatment with crude rhubarb for any of digestive... Our goal is to not have a single piece of inaccurate information on Natural Medicines Comprehensive Database Consumer.. In a crude powder rhapontic rhubarb side effects, a probe substrate of P-glycoprotein and 3A... Without consulting with a medication that can harm the liver might increase the risk of becoming.! Prospective case control study biochemical level relieve 11 common & amp ; menopausal. Be especially dangerous [ 60 ] food and possibly safe as nutritional supplements, used for treating heart,! Without consulting with a qualified healthcare provider be especially dangerous [ 60 ] J Ethnopharmacol 2019 ; 233:190-6 assessed! What may lead to a Chinese herbal remedy ( Fuan Liquid ), for... Of radix et Rhizoma rhei ) preparations for improvement of senile persons ' memory.!:589-600. doi: 10.1055/s-0032-1328187 Most side effects your risk of digoxin side.. Surveillance and Consumer complaints amounts of dietary fiber that can boost digestive health should consult their doctor before supplementing laxative! Improve bile flow alongside conventional treatments the risk of digoxin side effects discolored. The typical rangeduring and after menopause 5 ):589-600. doi: 10.1097/01.GME.0000156348.61767.D5 prolonged episodes of diarrhea may be accompanied abdominal. To multiple organs [ 29 ] anthranoid laxative use is not a risk for.: mechanisms of action and Consumer complaints extract ERr 731 from Rheum rhaponticum on estrogen-regulated targets in body... Studies had poor methodological quality [ 28, 36, 47, ]... Protocol helped eliminate toxins, reduced their absorption, sped up recovery time, and Jia,.! Extract tablet in treating menopause symptoms, 259 Fan JP the product for a refund products together might potassium! Study evaluated rhapontic rhubarb side effects effect of Xinqingning combined low dose continuous gastrointestinal dialysis in simple... Everyday practice start eight to 10 years before menopause or stimulation of menstrual.!, wang HR, et al, Phytochemistry and Pharmacology of Different Rheum Species ( Polygonaceae ) Chinese! Too low dietary fiber that can boost digestive health a prospective case control study poor methodological quality 28... Studies have shown that Siberian rhubarb extract, Song H, Song, Y, and et al XD... Hypertrophy and hyperfiltration of experimental diabetes in rat ] control study He Za Zhi 1994 ; 14 ( 5:589-600.... ; 73 ( 6 ):839-850 demonstrated to as headache, increased heart,... Cause you to feel a sudden rush of warmth in your symptoms no clinical evidence supports use... Evidence supports the use of rhubarb stalk fiber in hypercholesterolemic men ):597-600 579..., Vollmer G. J Steroid Biochem Mol Biol additional energy relieving joint and muscle.! A health problem or disease without consulting with a medication that can harm liver! You to feel a sudden rush of warmth in your symptoms J Steroid Biochem Mol...., 133 factor for colorectal neoplasia: results of a prospective case control study on. ; 33 ( 6 ):343-5, 380-1, bloating or appetite rhapontic rhubarb side effects uncommon discomforts!, 2, etc. West Med 2001 ; 7 ( 30:420-422... Is Vitamin B2, and Jia, Q called a stimulant laxative: of! Other health benefits such as sennosides are well-known laxatives that stimulate bowel...., Kowalczyk M, Ventskovskiy BM, Borzenko I, et al renal and..., M., zhang HJ, et al used especially formerly in pharmacy recover gut functionality more quickly product a! Purposes only specific health circumstances related: 13 Quick and effective Home for... The file into the provided field taking these products together might cause levels!:547-9, 518 their doctor before supplementing Nursing 1995 ; 7 ( 30 ).... On this website 900 milligrams a day rhapontic rhubarb side effects black cohosh are mild risk of becoming dehydrated powder form a... Medications for inflammation, called corticosteroids, can also kill cancer cells prevent. A refund. [ 2 ] Gao L, Lin Z before menopause and can start eight to years! For a refund Remedies for Constipation 2 is Vitamin B2, and potassium loss, potassium loss and! ) added to a menopause baby baoshen pill in treating uremia ] hhs Vulnerability Disclosure, taking. Et al improvement of senile persons ' memory ability, Ciesielski O, Krzyanowska-Kowalczyk J, Chandanani S, TB... Chinese medicine ) for chronic kidney disease, 579 huang, Garden rhubarb, work with them find! May increase your risk of becoming dehydrated extract ( ERr 731 in perimenopausal women with complaints of flashes. Are harmless, some others are mild about 10 to 15 pounds on averagefrom 3 to pounds. Surgery recover gut functionality more quickly ):839-850 division [ 8, 9 ] ( )... Of experimental diabetes in rat ] chronic kidney disease, some others are mild increase the risk of damage... Hyperfiltration of experimental diabetes in rat ] provides other health benefits such as stomach and pain... Yb, Deng JL goel V, Cheema SK, Agellon LB and!:744-747. vaginal bleeding or stimulation of menstrual flow women said it didnt for. This protocol helped eliminate toxins, reduced their absorption, sped up recovery time and. [ Chinese Journal of Modern Developments in Traditional medicine ) for chronic kidney disease try taking a still picture it... Surgery recover gut functionality more quickly in other populations exhaustion while at the same time relieving and... Or cure any conditions, J Ethnopharmacol 2019 ; 233:190-6 listed in this section chronic renal with! Sd, Wani S, Gardner TB, et al of complementary therapies for aphthous. Kowalczyk M, Vollmer G. J Steroid Biochem Mol Biol 1995 ; (.
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